释义 |
Schüller–Christian Path.|ˈʃʊlə ˈkrɪstɪən| The names of Artur Schüller (1874–1958), Austrian neurologist, and Henry Asbury Christian (1876–1951), U.S. physician, who each described the condition (in Fortschritte a.d. Geb. d. Roentgenstrahlen (1916) XXIII. 12 and Contrib. Med. & Biol. Res. (1919) I. 390 respectively), used attrib. to designate a pathological condition, often associated with diabetes insipidus, in which masses of lipid-laden histiocytes develop, usu. in the bones. Also in comb. with the name of Alfred Hand (1868–1949), U.S. pædiatrician.
[1925C. Q. Thompson et al. in Arch. Internal Med. XXXVI. 650 As Christian's excellent paper has formed and will continue to form the basis for studies of this baffling syndrome, it is suggested for the sake of simplicity the name Christian's syndrome be used.] 1935Brit. Jrnl. Surg. XXII. 810 It is that which is known to the medical profession as Schüller-Christian's syndrome. Ibid. 811 An excess of cholesterol in certain body tissues is the primary factor in the production of the clinical syndrome of lipoid granulomatosis (Schüller-Christian's disease). 1953Schüller-Christian disease [see histiocytosis] 1960Hand-Schuller-Christian disease [see lipid storage s.v. lipid 2]. 1974R. M. Kirk et al. Surgery vii. 151 Schuller-Christian disease. Histiocytes contain cholesterol. |