| 释义 |
proteinosis Path.|prəʊtiːˈnəʊsɪs|
[mod.L., ad. G. lipoid)proteinose (E. Uhrbach in J. Jadassohn Handb. der Haut- und Geschlechtskrankheiten (1932) XII. 336): see protein and -osis.]
The abnormal accumulation or deposition of protein in tissue.
1937Arch. Dermatol. & Syphilol. XXXV. 357 A subsequent microscopic examination revealed the tinctorial and cellular features of lipoid proteinosis. 1954Ann. Internal Med. XLI. 163 Lipoid proteinosis is a peculiar abnormality of fat deposition characterized by the appearance of white or yellow plaques and nodules in the skin and mucous membranes, producing hoarseness due to vocal chord involvement. 1958New England Jrnl. Med. 5 June 1123 (heading) Pulmonary alveolar proteinosis. 1961Lancet 30 Sept. 733/2 A man aged 36 gave a 2-year history of increasing breathlessness with diffuse shadowing on the chest radiograph. 15 months after the onset of symptoms a lung biopsy..showed that he had pulmonary alveolar proteinosis. 1974Arch. Dermatol. CX. 594/2 This finding suggests that lipid accumulation in lipoid proteinosis lesions is not due to a primary defect in lipid metabolism, but could be due to secondary adherence to glyco⁓proteins. |