| 释义 |
aromatase, n. Biochem.
Brit. |əˈrəʊməteɪz|, U.S. |əˈroʊməˌteɪs|, |əˈroʊməˌteɪz|
[‹ aromat- (in either aromatization n. or aromatize v.) + -ase suffix.]
An enzyme that catalyses an aromatization reaction; spec. one that converts androgens to oestrogens by aromatization.
1959Biochimica et Biophysica Acta 36 103 (caption) ‘Prephenic aromatase’ has been suggested (personal communication from Dr. B. D. Davis) as the name for the enzyme aromatizing PPA [= prephenic acid] to phenylpyruvate. 1973Amer. Jrnl. Obstetr. & Gynecol. 117345 (title) Evaluation of placental steroid 3-sulfatase and aromatase activities as regulators of estrogen production in human pregnancy. 1983N. G. Simon in E. C. Simnel et al. Aggressive Behavior ii. 20 (caption) Testosterone is enzymatically converted to estradiol by aromatase. 2004J. Ogden Understanding Breast Cancer xii. 102 Aromatase inhibitors such as anastrozole (Arimidex)..and have been shown to be even more effective than tamoxifen in cutting the risk of cancer recurring in oestrogen-positive cancers. |