| 释义 |
plasmalogen Biochem.|plæzˈmæləʊdʒən|
[a. G. plasmalogen (Feulgen & Voit 1924, in Pflügers Arch. f. ges. Physiol. CCVI. 399): see plasmal and -ogen.]
Any of a class of phospholipids that yield an aldehyde on mild hydrolysis and are now regarded as having an unsaturated ether linkage in place of one of the fatty acid ester linkages.
1925Chem. Abstr. XIX. 1155 Throughout the protoplasm of animal tissues there is to be found, very widely disseminated, a substance of lipoid character, insol. in water but sol. in org. solvents and extractable by alc., termed plasmalogen. When subjected to acids..this substance is split into undetd. components termed plasmal. 1964A. White et al. Princ. Biochem. (ed. 3) v. 75 Plasmalogens without a nitrogenous base, i.e., α, β- unsaturated ethers of phosphatidic acid, have also been reported in animal tissues, e.g., liver. 1964[see cephalin2]. 1968Passmore & Robson Compan. Med. Stud. I. x. 5/1 The plasmalogens have an unsaturated ether group, rather than an ester group, on the α position [of the glycerol molecule]. Those of ethanolamine and choline form a big proportion of the phospholipids of brain and heart.
Hence ˌplasmaloˈgenic a.
1939Chem. Abstr. XXXIII. 8635 This fraction contg. plasmalogenic acid (I) increases with the time of alk. hydrolysis. 1962Compar. Biochem. & Physiol. V. 220 (caption) The arrow..points out the phosphatidic acid plasmalogen (plasmalogenic acid) characteristic of blood⁓fed leeches. 1970R. W. McGilvery Biochem. xxiv. 600 The vinyl ether group [in plasmalogens] is believed to be formed by reduction of a diglyceride... The resultant plasmalogenic diglyceride reacts..to form phosphatidal⁓choline..in the same way that ordinary diglycerides react in the formation of the phosphatidylcholines. |