| 释义 |
Pick's disease|ˈpɪks dɪˈziːz|
1. [f. the name of Friedel Pick (1867–1926), Austrian physician.] A form of multiple serositis characterized by constrictive pericarditis, hepatomegaly, and ascites.
1900Dunglison Dict. Med. Sci. (ed. 22) App. 1314/2 Pick's disease, pseudocirrhosis of the liver, sometimes accompanying adhesive pericarditis. 1935Lancet 14 Sept. 602/1 The prognosis of Pick's disease without surgical treatment is unfavourable for health and in some cases for life. 1940E. Rosenthal Dis. Digestive Syst. iii. 278 Such a perihepatitis may be the result of liver disease or may accompany ‘pericarditic pseudocirrhosis’ (Pick's disease). 1959Bailey & Love Short Pract. Surg. (ed. 11) xx. 376 The best example of perisplenitis occurs in association with multiple serositis (Pick's disease).
2. [f. the name of Arnold Pick (1851–1924), Austrian psychiatrist and neurologist.] A condition, chiefly afflicting persons in late middle age, which is characterized by deterioration of intellect and judgement, speech disturbance and eventual dementia, and is caused by progressive atrophy of the frontal and temporal lobes of the brain.
1931Lancet 20 June 1331/2 Pick's disease is a slowly progressive dementia starting usually in the sixth decade and accompanied by focal manifestations. 1935Jrnl. Nervous & Mental Dis. LXXXII. 71 High blood pressure and arteriosclerosis are peculiarly absent in Pick's disease. 1955H. H. Merritt Textbk. Neurol. vi. 417 The cardinal symptoms of both Pick's and Alzheimer's disease are progressive dementia and disturbances in the speech. 1974Passmore & Robson Compan. Med. Stud. III. xxxv. 76/1 The underlying cerebral atrophy..is restricted to the frontal and temporal lobes in Pick's disease. 1976Smythies & Corbett Psychiatry vii. 126 Pick's disease is marked by a rapid and profound blunting of social judgement. |