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单词 phthalylsulphathiazole
释义 phthalylsulphathiazole Pharm.|ˌfθælɪlsʌlfəˈθaɪəzəʊl|
Also (U.S.) -sulfa-.
[f. phthalyl + sulphathiazole.]
A sulphonamide drug, HOOC·C6H4·CONH·C6H4·SO2NH·C3H2NS, that is a whitish powder and is used to suppress bacteria in the gastro-intestinal tract.
1943Poth & Ross in Federation Proc. II. 89/2 An extension of the studies on acylated sulfonamides as intestinal antiseptics..has uncovered another effective derivative of this series of drugs, phthalylsulfathiazole.1961M. Hynes Med. Bacteriol. (ed. 7) x. 138 Inabsorbable compounds (e.g., phthalyl-sulphathiazole) are available for oral treatment of intestinal infections.1970Passmore & Robson Compan. Med. Stud. II. xx. 25/1 Succinylsulphathiazole and p[h]thalysulphathiazole are both poorly absorbed from the gastrointestinal tract and have been advocated for the treatment of intestinal infections and for prophylactic use in elective operations on the colon.1977Proc. R. Soc. Med. LXX. 482/1 The preliminary results of this study have shown that a combination of oral phthalylsulphathiazole and metronidazole for preparation of the bowel for surgery reduces the incidence of postoperative infection compared with phthalylsulphathiazole alone.
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