| 释义 |
perhexiline Pharm.|pəˈhɛksɪliːn|
[Arbitrary blend of piperidine and hexyl.]
A white crystalline solid which is a vasodilator, tablets of the maleate of which are given for the relief of angina pectoris; 2-(2,2-dicyclohexylethyl)piperidine, C19H35N.
1969Current Therapeutic Res. XI. 99 A clinical study was undertaken to explore the effectiveness of perhexiline in relief of angina pectoris. 1970Chest LVIII. 579/2 There was slowing of the heart rate as a result of the infusion of perhexiline. 1977Lancet 30 July 260/1 The Committee on Safety of Medicines has circulated an adverse-reactions warning about perhexiline maleate (‘Pexid’). Ibid. 12 Nov. 1028/1 During treatment with perhexiline maleate hypoglycæmia, hyperlipidæmia, and liver dysfunction have been reported. |