| 释义 |
peptidolysis Biochem.|ˌpɛptaɪˈdɒlɪsɪs|
[f. peptide + -o + -lysis.]
The degradation of a polypeptide into smaller peptides or amino-acids. Cf. peptolysis. So ˌpeptidoˈlytic a.
1970Nature 25 July 337/2 Studies on the mechanism of action of peptidolytic enzymes..have made much use of their ability to hydrolyse esters as well as amides. 1971Ibid. 25 June 495/2 Both sets of workers compared these data with kinetic results from peptidolytic reactions. 1972Biochim. & Biophys. Acta CCLXV. 70 Cleavage, for example, of a 50 000-dalton peptide into fragments of 44 000 and 6000 daltons, respectively, can clearly be detected... Such peptidolysis can be observed only after dissolution of the protein by the detergent, since separated peptide fragments otherwise tend to remain associated through hydrophobic interactions. |