| 释义 |
pentobarbitone Pharm.|pɛntəʊˈbɑːbɪtəʊn|
[f. pentane + -o + barbitone.]
The synthetic compound 5-ethyl-5-(1-methyl-butyl)-barbituric acid, which is widely used as a sedative-hypnotic and anticonvulsant drug, usu. in the form of its sodium salt, C11H17N2O3Na, a white crystalline powder often known by the proprietary name Nembutal; = pentobarbital. So pentobarbitone sodium, sodium pentobarbitone.
1938S. Alstead Poulsson's Text-bk. Pharmacol. & Therapeutics (ed. 2) i. 41 Nembutal, pentobarbitone, sodium ethyl-methyl-butyl barbiturate. 1950Brit. Med. Jrnl. 25 Mar. 706/1 The child is premedicated with atropine..and pentobarbitone. 1960Times 6 Jan. 9/5 Once the rhino is dazed, two more rangers will move in with syringes to pump 600 c.c. of pentobarbitone sodium into the hide. 1962Lancet 29 Dec. 1379/1 Progressive fall in temperature down to cardiac arrest, seen in two rabbits subjected to surface cooling in a deep-freeze at 0°C while under pentobarbitone anæsthesia. 1971Nature 21 May 182/1 The dog was anaesthetized with pentobarbitone and heparin was used as an anticoagulant. 1975Ibid. 4 Sept. 62/1 Each rat was killed with an overdose of sodium pentobarbitone. |