| 释义 |
resolvase, n. Biochem.|rɪˈzɒlveɪz|
[f. resolve v. + -ase.]
An enzyme which promotes the resolution of two transposons contained in a cointegrate.
1981R. R. Reed in Cell XXV. 713/2 These results have led to the suggestion that the regulatory role of the tnpR product upon expression of the divergently transcribed tnpA and tnpR genes and its recombinational activity may both result from specific binding to a single site... To emphasize this major function, the tnpR protein has been renamed ‘resolvase’. 1983J. R. S. Fincham Genetics x. 270 Reciprocal recombination, specifically catalysed in the recombination sequence of the transposon by the tpnR product (‘recombinase’ or ‘resolvase’), resolves the cointegrate into two separate plasmids. 1988Nature 28 Apr. 862/1 Resolvase catalysed substantial relaxation of the mutant substrate into topoisomers of reduced negative superhelicity. |