| 释义 |
pantothenic, a. Biochem.|pæntəʊˈθɛnɪk|
[f. Gr. πάντοθεν from every side (f. παντο- panto-) + -ic.]
pantothenic acid: an oily, optically active carboxylic acid, HOCH2C(CH3)2CHOH·CO·NH(CH2)2COOH, which is widely distributed in plant and animal tissues (mainly in combined form as coenzyme A), is essential for the growth of yeast and certain bacteria, and is a member of the vitamin B complex.
1933R. J. Williams et al. in Jrnl. Amer. Chem. Soc. LV. 2925 We can safely regard the activity [in stimulating the growth of yeast] as due to a single acid. Since this acid appears to be of very widespread occurrence..we have tentatively called it ‘pantothenic’ acid. 1953J. Ramsbottom Mushrooms & Toadstools viii. 82 Some strains of Saccharomyces cerevisiae require inositol, biotin, aneurin, pantothenic acid and other factors. 1960Times 2 July 2/6 Certain..vitamins [in royal jelly]..are almost entirely members of the B-complex, and include an unusually high proportion of pantothenic acid. 1974Passmore & Robson Compan. Med. Stud. III. i. xxiv. 30/1 Pantothenic acid deficiency has been considered, on the basis of therapeutic trials, to be the cause of the burning feet syndrome.
Hence pantoˈthenate, the anion, or an ester or salt, of pantothenic acid.
1941Chem. Abstr. XXXV. 3606 [α] 24 / d for the pantothenate ion is calcd. to be -26·8°. 1955Sci. News Let. 1 Oct. 211/1 The cancer cells, Dr. Eagle finds, need these seven vitamins: choline, folic acid, nicotinamide, pantothenate, pyridoxal, riboflavin and thiamine. 1974R. W. Doskotch in W. O. Foye Princ. Med. Chem. xxv. 613/2 The commercial synthesis of calcium pantothenate starts with isobutyraldehyde and formaldehyde. |