| 释义 |
oxacillin Pharm.|ɒksəˈsɪlɪn|
[f. is)oxa(zole (s.v. iso- b) + penicillin.]
A semisynthetic penicillin, C19H18N3O5NaS.H2O, that is used as an alternative to methicillin, having the same resistance to penicillinase and being in addition resistant to acid so that it can be taken orally; (5-methyl-3-phenyl-4-isoxazolyl)-penicillin sodium. Also called oxacillin sodium and sodium oxacillin (in the British and U.S. pharmacopœias respectively).
1962Proc. Mayo Clinic XXXVII. 137, 5-Methyl-3-phenyl-4-isoxazolyl penicillin (Prostaphlin*). [Note] *Trade name of Bristol Laboratories, Inc... Since this paper was prepared for publication, ‘oxacillin’ has been adopted as the generic name of this drug. 1963New & Non-Official Drugs 148 Sodium oxacillin is a semisynthetic penicillin salt for oral administration. 1967Martindale's Extra Pharmacopoeia (ed. 25) 994/1 Oxacillin sodium is more resistant to destruction by the acid gastric secretion than benzylpenicillin or methicillin sodium. 1970Atlantic Monthly Mar. 50 He was also given heavy doses of antibiotics, including a gram of chloramphenicol, a gram of oxacillin, [etc.]. |