| 释义 |
osteoclastoma Path.|ˌɒstiːɒklæˈstəʊmə|
Pl. -omas, -omata.
[f. osteoclast s.v. osteo- + -oma.]
A giant-cell tumour of bone characterized by the presence of numerous osteoclast-like cells; orig. applied to a variety of mostly benign tumours, but now restricted to a type that is often malignant.
1926Jrnl. Path. & Bacteriol. XXIX. 399 (heading) A case of osteoclastoma (myeloid sarcoma, benign giant-cell tumour) with pulmonary metastasis. 1931Brit. Jrnl. Surg. XIX. 242 Generalized osteitis fibrosa with multiple osteoclastomata. 1948[see myeloma]. 1961Lancet 30 Sept. 751/2 Osteoclastomas respond well to irradiation. 1974Passmore & Robson Compan. Med. Stud. III. i. xxvi. 31/1 Giant cell tumour (osteoclastoma)... The nature of the cells is not definitely known, but the possibility that the giant cells are osteoclasts has led to the alternative name, osteoclastoma. |