| 释义 |
obese, a.|əʊˈbiːs|
[ad. L. obēs-us that has eaten itself fat, stout, plump, pa. pple. of obedĕre to eat away, f. ob- (ob- 1) + edĕre to eat.
Rare before 19th c.; in Johnson without quot.]
Very fat or fleshy; exceedingly corpulent.
1651Biggs New Disp. ⁋251 More obese and plethorick bodies. 1654Gayton Pleas. Notes i. iii. 8 One said of an Over-Obese Priest that he was a great Arminian; grant, quoth a second, that he be an Arminian, I'll swear he is the greatest that ever I saw. 1822T. Taylor Apuleius 316 A back obese, and animated breast. 1848C. Brontë J. Eyre iv. (1857) 30 A woman of robust frame, square shouldered,..and though stout, not obese. 1864F. Oakeley Hist. Notes 85 An obese octavo, extending to six hundred closely printed pages.
b. Entom. (See quot.)
1826Kirby & Sp. Entomol. IV. 260 Obese..Unnaturally enlarged and distended, as if from disease or too much food.
Hence oˈbesely adv.; oˈbeseness (= next).
1653Gauden Hierasp. 560 The fatnesse of Monkes, and the obeseness of Abbots. 1654R. Codrington tr. Iustine xxxviii. 456 He..was..short in stature, and by the obeseness of his strutting belly, more like unto a Beast then to a man. 1820Moore Fables v. 79 Her fat locusts, like a cloud Of pluralists, obesely lowering. 1891G. Meredith One of our Conq. I. ix. 151 Obeseness is the most sensitive of our ailments.
▸ Genetics. A gene first identified as an autosomal recessive mutation in phenotypically obese mice, and later found to code for the protein leptin; the murine leptin gene. Freq. attrib.
Now usually italicized in technical sources.
1950A. M. Ingalls et al. in Jrnl. Heredity 41 317 (title) Obese, a new mutation in the house mouse. 1975Metabolism 24 573 By mating mice heterozygous for the recessive gene, obese (ob/+) (+/+), with mice homozygous for the recessive gene, dwarf (+/+)(dw/dw), and subsequent mating of the offspring, mice homozygous for both the obese and dwarf gene were obtained. 1987Genomics 1 167/1 This places met near the obese locus in a region of mouse chromosome 6 that appears to be homologous with the long arm of human chromosome 7. 1998Jrnl. Endocrinol. 15979 Leptin, the recently identified product of the obese gene, may very well be an integral signal which regulates neuroendocrine responses in times of food deprivation. |