| 释义 |
nystatin Pharm.|ˈnaɪstətɪn|
[f. the name of New York State, U.S.A., where it was developed + -in1.]
A yellow antifungal substance, C46H77NO19, that is produced by the growth of the bacterium Streptomyces noursei and is used locally in the treatment of moniliasis, esp. when caused by Candida albicans, and of anal and vaginal infections.
1952Arch. Pediatrics LXIX. 414 Hazen et al. have shown that an antibiotic called fungicidin, Nystatin®, has inhibited coccidioides immitis spherules at 6·25 micrograms per milliliter. [The name Nystatin is not in fact registered as a trade mark at the U.S. Patent Office.] 1953Science 29 May 609/2 The senior authors [sc. Brown & Hazen] have given the name Nystatin to their product fungicidin. It is being manufactured by E. R. Squibb and Sons under this name. 1962E. O. Morris in Hawthorn & Leitch Recent Adv. Food Sci. I. 33 Yeasts appear to be particularly troublesome and it has been suggested that these organisms may be inhibited by the use of nystatin. 1974R. N. Richards Venereal Dis. 104/1 The diagnosis of monilia was made and she responded well to the insertion of nystatin tablets in her vagina twice daily. |