释义 |
nialamide Pharm.|naɪˈæləmaɪd| [f. the proprietary name Niamid by insertion of -al.] A crystalline hydrazide, C16H18N4O2, which is a monoamine oxidase inhibitor used as an antidepressant.
1959Proc. Soc. Exper. Biol. & Med. CI. 832 (heading) Pharmacological studies with nialamide, a new antidepressant agent. 1960A. Carlsson et al. in J. R. Vane et al. Adrenergic Mechanisms 434 Fig. 1 shows the action of nialamide, which is a very potent and long-acting monoamine oxidase inhibitor though its action sets in fairly slowly. 1971Brit. Med. Bull. XXVII. 28/2 First nialamide..and then tranylcypromine..began to be used for the treatment of depression. |