| 释义 |
mevalonic, a. Chem.|mɛvəˈlɒnɪk|
[f. methyl + valeric a. + lactone + -ic.]
mevalonic acid: 3,5-dihydroxy-3-methylvaleric acid, C6H12O4, a crystalline compound which is a growth factor for some lactobacilli and is a precursor of cholesterol in animals and of carotenoids in plants.
1957D. E. Wolf et al. in Jrnl. Amer. Chem. Soc. LXXIX. 1486/1 The name ‘mevalonic acid’ is now being used to designate β,δ-dihydroxy-β-methylvaleric acid. 1962H. A. Krebs in A. Pirie Lens Metabolism Rel. Cataract 351 The reaction sequence is inhibited by cholesterol itself and some of its immediate precursors by stopping an early stage, probably that giving rise to mevalonic acid. 1973Plant Physiol. LI. 110/1 Mevalonic acid-2-14C was readily incorporated into the free, esterified, and glycosidic sterol fractions of tobacco..seedlings.
Hence meˈvalonate, the anion of mevalonic acid.
1959A. White et al. Princ. Biochem. (ed. 2) xix. 488 Mevalonic kinase..catalyzes the formation of phosphomevalonic acid and ADP from mevalonate and ATP. 1971Hunter & Rose in Rose & Harrison Yeasts II. vi. 243 Brewer's solubles were shown to contain a compound which could replace acetate in sterol biosynthesis, and this compound was shown to be mevalonate. |