| 释义 |
methisazone Pharm.|mɛˈθɪsæzəʊn|
[f. methyl + isatin + thiosemicarbazone (cf. the chemical name given in def.).]
A fine orange-yellow powder that has prophylactic activity against smallpox; N-methylisatin β-thiosemicarbazone, C10H10N4OS.
1964Brit. Med. Jrnl. 5 Sept. 621/1 Methisazone breaks new ground in the rational therapy of virus infections. 1966New Scientist 17 Nov. 336/3 Dr D. J. Bauer and Dr K. Apostolov..had shown methisazone (‘Marboran’) to be active against certain adenoviruses growing in tissue culture. 1970Passmore & Robson Compan. Med. Stud. II. xx. 36/1 In man, methisazone has been shown to be effective in preventing disease in contacts of patients suffering from smallpox... Methisazone has not been shown to be effective in treating established infections. |