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单词 mephenesin
释义 mephenesin Pharm.|məˈfɛnəsɪn|
[f. methyl + phenyl + cresol + -in1.]
A colourless crystalline compound, CH3·C6H4O·CH2CH(OH)CH2OH, which is used as a muscle-relaxant in the treatment of spastic, hypertonic, and hyperkinetic conditions, and as a tranquillizer.
1952Brit. Pharmaceut. Codex 1949 Suppl. 40 Mephenesin consists of 3-(2-methylphenoxy)propane-1:2-diol.1955Sci. News Let. 16 July 40/3 In the great majority of 109 cases [of cerebral palsy] treated before dental surgery with mephenesin,..the drug produced feelings of well-being and relaxation, and nervousness diminished or disappeared.1962J. H. Burn Drugs, Med. & Man xii. 127 Another study was made by other workers to test the claim that the drug mephenesin exerts a specific effect on subjective anxiety and feeling of tension, and also on objective manifestations of this state.1972Neuro-pharmacology XI. 733 Amino-oxyacetic acid did not protect rats against the audiogenic seizures that constitute the barbiturate abstinence syndrome whereas mephenesin..did provide protection.
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