| 释义 |
mecamylamine Pharm.|ˌmɛkəˈmaɪləmiːn|
[f. methyl + *cam(phane + -yl + amine.]
A potent ganglion-blocking drug, 3-methylaminoisocamphane, C11H21N, which is used in treating hypertension.
1955Sci. News Let. 29 Oct. 281/1 A nerve-blocking drug called mecamylamine. 1956Arch. Internal Med. XCVII. 561/1 Such side effects as constipation were just as prominent with the small completely absorbed doses of mecamylamine as with the relatively large poorly absorbed doses of other ganglion-blocking agents. 1968L. Gyermek in A. Burger Drugs Affecting Cent. Nervous Syst. I. iv. 290 Mecamylamine depresses the vasomotor center independently of its ganglionic blocking action. 1971Nature 17 Sept. 207/1 Previous work in this laboratory with monkeys trained to puff cigarette smoke showed that mecamylamine, a nicotinic-blocking agent, reduced their smoking. 1974M. C. Gerald Pharmacol. viii. 159 Ganglionic blocking agents such as mecamylamine (Inversine)..prevent cholinergic transmission at the autonomic ganglia. |