| 释义 |
Zollinger–Ellison syndrome Path.|ˈzɒlɪndʒər ˈɛlɪsʌn|
[Named after M. Zollinger (b. 1903) and E. H. Ellison (1918–70), American physicians, who described the syndrome in 1955 (Ann. Surg. CXLII. 709).]
A syndrome characterized by excessive gastric acid secretion (producing recurrent peptic ulcers) associated with a gastrin-secreting tumour or hyperplasia of the islet cells of the pancreas.
1956Eiseman & Maynard in Gastroenterology XXXI. 302 For the sake of simplicity we propose this clinical entity be called the Zollinger-Ellison syndrome. 1960Jrnl. R. Coll. of Surgeons of Edin. V. 191 Since that time [sc. 1955] over 100 instances of co-existent peptic ulcer and islet cell tumours have been described and the association appears to constitute a clinical entity called, by general consent, the ‘Zollinger-Ellison syndrome’. 1962[see islet 3]. 1974R. M. Kirk et al. Surgery vi. 85/1 In the Zollinger-Ellison syndrome, ulcers may occur at the duodenojejunal junction. |