| 释义 |
Letterer–Siwe, n. Path.|ˌlɛtərəˈsiːvə|
[The names of Erich Letterer (b. 1895) and Sture August Siwe (b. 1897), German physicians.]
Used attrib. and in the possessive to designate a usually fatal histiocytosis of soft tissues, occurring in early childhood.
1936Abt & Denenberg in Amer. Jrnl. Dis. Children LI. 499 (heading) Letterer-Siwe's disease. 1949Amer. Jrnl. Path. XXV. 49 These cases fulfill the requirements for Letterer-Siwe's disease as formulated by Abt and Denenberg. 1953L. Lichtenstein in A.M.A. Arch. Path. LV. 102 The conditions previously designated eosinophilic granuloma of bone, ‘Letter-Siwe disease’ and ‘Schüller-Christian disease’ are interrelated manifestations of a single malady. The name ‘histiocytosis X’ is suggested as a provisional broad general description for this nosologic entity. 1961R. D. Baker Essent. Path. xviii. 489 Reticuloendotheliosis (Letterer-Siwe disease) is either a hyperplasia or a true neoplasm of the macrophage system of infants, with enlargement of the liver and spleen. 1986Times 13 June 13/2 Doctors have to be on the look-out for..the very rare hystiocytosis [sic] X (Letterer-Siwe disease). |