| 释义 |
‖ leproma Path.|lɛˈprəʊmə|
Pl. lepromas, lepromata.
[f. lepra, on the analogy of words like sarcoma.]
A leprous tubercle.
1895N. Walker tr. Hansen & Looft's Leprosy ii. 5 The leprous nodes [of nodular Leprosy] or nodular Lepromata are of different size and colour; their consistence is at first firm and hard... Their form is usually semi-spherical, but they are often oblong. 1898P. Manson Trop. Diseases xxvi. 385 The leproma, the nerve lesions, and the lepra cell. 1947R. G. Cochrane Pract. Textbk. Leprosy viii. 81 We are convinced..that the majority of lepromas commence from pre-lepromatous macules..; some, however, develop from the simple macular lesions. 1970G. J. Hill Leprosy in Five Young Men iv. 103 The mixture [sc. lepromin] is essentially a sterile emulsion of lepromas—that is, nodules excised from patients with lepromatous leprosy.
Hence leˈpromatous a., of the nature of a leproma; characterized by or exhibiting lepromas: used spec. to designate one of the two principal forms of leprosy (see quot. 1938).
1898P. Manson Trop. Diseases xxvi. 397 The eyes also [in a leper] are sooner or later attacked, lepromatous growth spreading from the conjunctiva on to the cornea. 1938Internat. Jrnl. Leprosy VI. 390 [Report of the Sub⁓committee on Classification of the First International Congress on Leprosy.] Objections have repeatedly been raised to both of the current names of the two types [of leprosy] (i.e., ‘neural’ and ‘cutaneous’)... It is the opinion of the committee... (b) That because ‘cutaneous’ has proved particularly confusing its use should be discontinued, and replaced by the term ‘lepromatous’. Ibid., Lepromatous (L) type.—All cases of the ‘malignant’ form of leprosy, relatively nonresistant and of poor prognosis, usually negative to leprolin, exhibiting lepromatous lesions of the skin and of other organs, especially the nerve trunks. 1947[see above]. 1962Lancet 26 May 1116/2 If the altered tissue response could be maintained by repeated b.c.g. vaccination, this might prove a beneficial adjunct to chemotherapy in lepromatous leprosy. 1970[see above]. 1971Nature 7 May 48/1 Leprosy, caused by Mycobacterium leprae, has two clinico⁓pathological forms: lepromatous, associated with impaired delayed hypersensitivity, and tuberculoid, with intact cutaneous reactivity. |