| 释义 |
kynurenic, a. Biochem.|kɪ-, kaɪnjʊˈrɛnɪk|
Also † cyn-.
[tr. G. kynuren-säure kynurenic acid (J. Liebig 1853, in Ann. d. Chem. LXXXVI. 125), f. Gr. κυν-, κύων dog + -uren-, irreg. f. οὖρον urine n.1: see -ic 1.]
kynurenic acid: a crystalline carboxylic acid, C10H7NO3, that results from the metabolism of tryptophan and is excreted in the urine of man and various animals; 4-hydroxyquinoline-2-carboxylic acid.
1872Jrnl. Chem. Soc. XXV. 1028 When heated by 265° kynurenic acid evolves pure carbon dioxide and melts to a brown liquid. 1889Roscoe & Schorlemmer Treat. Chem. III. v. 226 When..cynurenic acid is heated with zinc dust in a current of hydrogen, it is reduced to quinoline. 1946W. R. Fearon Introd. Biochem. (ed. 3) xvii. 351 Surplus dietary tryptophane is excreted in the urine as kynurenine (in rabbits), and as kynurenic acid (in dogs, rats, foxes and wolves). 1971Pediatrics XLVII. 47/1 This study measured urinary excretion of kynurenic acid..and xanthurenic acid.., two tryptophan metabolites via the kynurenine pathway, in 26 hospitalized children. |