释义 |
amitriptyline Pharm.|æmɪˈtrɪptɪliːn| [f. amino + tri- + he)ptyl s.v. heptane + -ine5: cf. protriptyline.] A tricyclic antidepressant drug with sedative properties, C20H23N, given as the hydrochloride.
1961Lancet 10 June 1287/2 Amitriptyline hydrochloride (‘Tryptizol’), a new antidepressant drug recently released to hospitals. 1963,1965[see protriptyline]. 1979Daily Tel. 27 Nov. 12/7 A third of the prescriptions were for imipramine and amitriptyline, and two-thirds of these were for branded products. 1981Approved Names (Brit. Pharmacopœia Comm.) 4 Amitriptyline, 3-(10,11-dihydro-SH-dibenzo[a,d]cyclohepten-5-ylidene)propyldimethylamine. 1982Sci. Amer. Mar. 112/3 Many of the antidepressant drugs employed in psychiatry, such as amitriptyline (Elavil), block the reuptake of neurotransmitters, but they are not stimulants and they do not induce euphoria. |