| 释义 |
progesterone Physiol.|prəʊˈdʒɛstərəʊn|
[ad. G. progesteron (W. M. Allen et al. 1935, in Klin. Wochenschr. 17 Aug. 1182/1), blend of progestin and its G. synonym luteosteron (K. H. Slotta et al. 1934, in Ber. d. Deut. Chem. Ges. LXVII. 1271), f. luteo-, repr. corpus luteum: see -sterone.]
A female steroid sex hormone, C21H30O2, which is secreted by the corpus luteum and also made synthetically, and is responsible for the cyclical changes in the uterus in the latter part of the menstrual cycle and also necessary for the maintenance of pregnancy. Also attrib. and Comb.
1935, etc. [see progestin]. 1949[see gestagen]. 1957Times 2 Dec. p. vi/2 When P.M.S. is used in conjunction with a steroid hormone progesterone it will bring maiden sheep into season to produce an extra crop of lambs in their second summer (six months earlier than normal). 1958[see gestagen]. 1961L. Martin Clin. Endocrinol. (ed. 3) ix. 229 Owing to its feeble progesterone⁓like action,..large doses must be given. 1965Lee & Knowles Animal Hormones ii. 20 As the corpus luteum matures, increasing amounts of progesterone are produced which depress the output of LH and LTH. 1966[see diosgenin]. 1968Times 11 Nov. 10/8 Udry and Morris suggest that of the two ovarian hormones, oestrogen tends to increase the likelihood of human sexual activity, and progesterone to decrease it. 1974Daily Colonist (Victoria, B.C.) 25 Aug. 26/2 By 1954, Chang and Pincus had found two progesterone hormones that worked. The birth-control pill was born. 1974Fertility & Sterility XXV. 575/2 The following trivial names are used in this paper:..progesterone (pregn-4-ene-3,20-dione). 1979Jrnl. R. Soc. Arts CXXVII. 417/2 It was possible to inhibit ovulation in experimental animals with progesterone. |