| 释义 |
idiotypic, a.|ɪdɪəʊˈtɪpɪk|
[f. *idiotype n. + -ic.]
†1. Chem. (Formerly at idio-.) Derived from the same compound by substitution. Cf. *idiotype n. 1. Obs.
1861[see *idiotype n. 1]. 1865Watts Dict. Chem. III. 242 Ammonia..is idiotypic with ethylamine, phenylamine, and all the organic bases [misprinted basis] derived from it by substitution, and these are idiotypic one with the other.
2. Genetics. Of or pertaining to an idiotype (*idiotype n. 2).
1924L. F. Barker tr. Siemens' Race Hygiene & Heredity v. 58 It was the study of the offspring of each individual red F2-plant that taught us to recognize what inheritance factors (idiotypic rudiments) lay concealed within the mother plant. 1961L. F. Brosnahan Sounds of Language vi. 147 Each child has its own proper inheritance which is revealed in his idiotypic capacity in speech development.
3. Immunol. Characteristic of or belonging to an idiotype (*idiotype n. 3).
1966J. Oudin in Jrnl. Cellular Physiol. LXVII. Suppl. i. 94/1 These antigenic specificities vary with individuals... Since each of them seems to be peculiar to antibodies against one antigen in an individual or a restricted class of individuals, they seem to deserve the name of idiotypic specificity, which indicates this notion of peculiarity. 1974Nature 4 Jan. 55/1 Individual mice respond to the p-azobenzoate and to the p-azophenylarsonate haptens by producing a population of serum antibodies with many idiotypic specificities. 1988Ibid. 20 Oct. 730/2 The T3.70 antibody is specific for an idiotypic determinant dependent on the expression of both α and β transgenic TCR [sc. T-cell receptor] chains.
Hence ˌidioˈtypically adv.
1924L. F. Barker tr. Siemens' Race Hygiene & Heredity v. 61 Among human beings, who are heterozygous with respect to many pairs of inheritance factors, idiotypically identical persons occur only..when two children arise from a single fertilized egg cell. 1974Nature 4 Jan. 56/2 The study of the response to phosphorylcholine in mice which have been idiotypically suppressed at different stages of ontogeny may indicate the origin of this clonal restriction. |