| 释义 |
alphavirus, n. Virol.
Brit. |ˈalfəvʌɪrəs|, U.S. |ˈælfəˌvaɪrəs|
[‹ alpha n. + virus n.; compare earlier name Arbovirus group A (see quot. 1971).]
Any member of the genus Alphavirus of antigenically related togaviruses that infect a wide range of mammals, birds, and other vertebrates, are transmitted by mosquitoes (or, rarely, other arthropods), and typically cause either a syndrome of fever, rash, and arthralgia (Old World alphaviruses) or a potentially fatal encephalitis (New World alphaviruses, or equine encephalitis viruses). Also (in form Alphavirus): the genus itself.
1971P. Wildy Classif. & Nomencl. Viruses 52 Current name... Arbovirus group A... Approved name... Alphavirus. 1971Lancet 16 Oct. 858/1 Chikungunya virus, a mosquito-borne group-A arbovirus (a togavirus of the alphavirus genus), was originally isolated in Africa from febrile patients with joint pains and a dengue-like rash. 1993Vet. Microbiol. 37 273 The equine encephalitis viruses are members of the genus Alphavirus, in the family Togaviridae. 2002Internat. Jrnl. Cancer 98 554 Replicons based on alphaviruses are emerging as candidate vectors for vaccination and gene therapy purposes. |