| 释义 |
proflavine Pharm.|prəʊˈfleɪviːn|
Also -in |-ɪn|.
[f. pro-2 + flavine.]
A yellowish-brown crystalline solid, 3,6-diaminoacridine, C13H11N3, which is used, in the form of an orange-red hydrated sulphate, as an antiseptic.
1917C. H. Browning in Brit. Med. Jrnl. 16 June 825/1 The Medical Research Committee's Department of Biochemistry and Pharmacology has..continued to give us valuable aid, especially by providing an experimental supply of ‘proflavine’. Ibid. 21 July 71/1 The name ‘proflavine’ has been suggested to us by the Medical Research Committee. 1917Lancet 3 Nov. 676/1 Proflavine..is..a preliminary product in the manufacture of acriflavine or flavine. 1945Times 7 Aug. 10/2 Other interesting items included 24,000,000 hypodermic tablets, 40,000,000 acriflavine and proflavine tablets. 1958Nature 11 Oct. 983/1 Proflavin, although not interfering with synthesis of deoxyribonucleic acid in phage-infected cells, inhibits the maturation of phage progeny particles. 1970Passmore & Robson Compan. Med. Stud. II. xviii. 41/1 Acridine dyes, e.g. proflavine, acriflavine, are more active than aniline dyes against Gram-positive bacteria, and are also active against Gram-negative bacilli. 1971D. J. Cove Genetics x. 137 The starting point of these studies was a 'phage strain which carried an rII mutation induced by the acridine proflavin. |