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单词 hydrochlorothiazide
释义 hydrochlorothiazide Pharm.|ˌhaɪdrəʊklɔərəʊˈθaɪəzaɪd|
[f. hydro- + chlorothiazide.]
A white crystalline powder which is a diuretic and saluretic sulphonamide drug, C7H8ClN3O4S2, analogous to chlorothiazide, and which is given orally in the treatment of œdema and as an adjuvant in the treatment of hypertension.
1958Experientia XIV. 458/1 Hydrochlorothiazide is the generic name of a new diuretic agent manufactured by CIBA.1959Lancet 13 June 1221/2 Hydrochlorothiazide promotes less bicarbonate excretion than chlorothiazide, but the loss of potassium after the two drugs is not significantly different.1965J. Pollitt Depression & its Treatment v. 72 In mild cases [of premenstrual depression]..Hydrochlorothiazide with potassium chloride (Hydrosaluric K) 25–75 mg. daily or on alternate days from 7–10 days premenstrually is effective.1968J. H. Burn Lect. Notes Pharmacol. (ed. 9) 105 Hydrochlorothiazide and hydroflumethiazide are ten times stronger than chlorothiazide.
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