| 释义 |
Hox, n.2 Genetics.
Brit. |hɒks|, U.S. |hɑks|
Forms: 19– Hox, 19– hox
[Shortened ‹homeobox n.]
More fully Hox gene. (The name of) a homeobox gene. Also, with distinguishing (freq. affixed) letter or numeral: any of several clusters of homeobox genes occurring in vertebrate genomes; any of the loci making up such a cluster.
1985C. P. Hart et al. in Cell 43 10/1 The restriction map of three of the homeo-box-containing phages showed them to constitute an overlapping that covered approximately 40kb of the mouse genome. This locus has been named Hox-2 (the second homeo box region described in the mouse genome). 1988Mouse News Let. Nov. 149 This new murine Hox gene..is expressed in the neural crest, in the mandibular arch and in the mesenchymal tissue that derive from it. 1992New Scientist 19 Sept. 41/1 Tampering with Hox genes in the fruit fly generally changes the identities of body segments, producing severe developmental abnormalities. 1993Cell 73 282/2 In the HoxB complex, Hoxb-2 (Hox-2.8) has an anterior boundary that maps to the basioccipital bone. 1995Nature 22 June 678/1 As the autopods (hands and feet) develop, Hoxd expression extends to most anterior and distal parts. 2000C. Tudge Variety of Life ii. v. 183 In general, the visible complexity of animals is reflected in the number and complexity of their Hox genes. |