| 释义 |
homozygote Biol.|hɒməʊˈzaɪgəʊt|
[f. homo- + zygote.]
A diploid individual that has identical alleles at one or more genetic loci. Also attrib. or as adj., homozygous.
1902Bateson & Saunders Rep. Evol. Comm. R. Soc. I. 126 Similarly, the zygote formed by the union of gametes having similar allelomorphs, may be spoken of as a homozygote. 1902W. Bateson Mendel's Princ. Heredity 23 This Aa is the hybrid, or ‘mule’ form, or as I have elsewhere called it, the heterozygote, as distinguished from AA or aa the homozygotes. 1903― in Nature 19 Mar. 463/1 The homozygotes will all have pink eyes. 1909R. H. Lock Rec. Progress in Study of Variation (ed. 2) vii. 185 Let the F1 plants, arising from the smooth yellow heterozygote grains, be crossed with the wrinkled white parent. 1927Haldane & Huxley Animal Biol. ii. 67 Homozygote parents. 1930R. A. Fisher Genet. Theory Nat. Selection i. 8 The heterozygote when mated to either kind of homozygote would produce both heterozygotes and homozygotes. 1949Darlington & Mather Elem. Genetics xiii. 276 If we breed a homozygote, or a group of like homozygotes, the offspring will be genetically..identical both with their parents and with one another. 1965T. Dobzhansky Heredity & Nature of Man v. 156 Persons who inherit this gene from both parents (homozygotes) die of fatal anemia.
Hence ˌhomozyˈgosis, the fusion of two genetically identical gametes; the state or condition of being homozygous; ˌhomozyˈgosity, the state or condition of being homozygous; the degree or extent to which an individual is homozygous with respect to its complement of genetic loci; ˌhomozyˈgotic a., of or pertaining to homozygosis; homozygous; ˌhomozyˈgotically adv.; homoˈzygous a., having identical alleles at one or more genetic loci.
1902Bateson & Saunders Rep. Evol. Comm. R. Soc. I. 152 The various homo- and hetero-zygous combinations. 1905W. Bateson in Rep. Brit. Assoc. 1904 348 The other possibility is that this phenomenon is due to simultaneous homozygosis of independent allelomorphs. 1916Mem. N.Y. Bot. Gard. VI. 349 Such a condition might also arise from inbreeding in which what is called ‘homozygosity’ might develop, giving similarity to the hereditary complex. 1925D. F. Jones Genetics Plant & Animal Improvement xv. 503 Only by bringing sexually reproducing organisms to a fairly high degree of homozygosity can there be any possibility of successfully predicting the outcome in particular matings. 1927Hereditas VIII. 77 Both V. tricolor and V. arvensis are homozygotic in respect of the modifying gene. Ibid. 147 One gene.., when homozygotically present, turns the full yellow to a yellowish white. 1942Nature 10 Jan. 54/2 Such self-mating gives immediate homozygosis. 1949Darlington & Mather Elem. Genetics xiii. 279 The homozygotic potential will remain as such so long as cross-breeding is absent or at least restricted to like homozygotes. 1957C. H. Waddington Strategy of Genes ii. 48 Further, gene-fixation and the passage to homozygosity, will be still more delayed if the environment does not remain perfectly uniform. 1969Sci. Jrnl. Dec. 86/2 Various disorders due to homozygosity for rare recessive genes..are much commoner in such inbred populations than in outbred populations. 1970Ambrose & Easty Cell Biol. x. 335 White-eyed females would only be observed if they were homozygous for this recessive gene. |