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单词 holocaine
释义 holocaine Pharm.|ˈhɒləʊkeɪn|
Also -cain.
[a. G. holocaïn, after cocaïn (now kokain) cocaine.]
The proprietary name of a synthetic derivative, C18H22N2O2, of p-phenetidine which resembles cocaine in its action and is used (in the form of the hydrochloride) as a surface anæsthetic for the eye; phenacaine.
1897Lancet 29 May 1466/1 A new alkaloid called holocaine..described as an effective anæsthetic for ophthalmic purposes.1899Amer. Jrnl. Med. Sci. CXVII. 121 The bactericidal power of holocain gives it the advantage that solutions..will keep themselves sterile.1910L. W. Fox Pract. Treat. Ophthalm. x. 287 The pain caused by this injection is very severe, and to mitigate this the eye should be thoroughly anaesthetized with holocain, cocain being insufficient.1955J. Adriani Selection of Anesthesia x. 98 Holocaine is prepared from para-ethoxy aniline (phenetidin).1968J. H. Burn Lect. Notes Pharmacol. (ed. 9) 62 Phenacaine (holocaine) is prompt in action and is used especially for the eye.
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