| 释义 |
tyrothricin Pharm.|taɪrəʊˈθraɪsɪn, -ˈθrɪsɪn|
[f. Tyrothrix (see quot. 1940), f. Gr. τυρό-ς cheese + θρίξ, τριχ- hair: see -in1.]
A preparation of gramicidin and tyrocidine which has antibiotic properties, esp. against Gram-positive bacteria, and has been used externally to treat local infections.
1940Hotchkiss & Dubos in Jrnl. Biol. Chem. CXXXVI. 804 Gramicidin will continue to be used as the name of the crystalline neutral substance described before. It is proposed here to apply the name tyrothricin to the bactericidal agent prepared as an alcohol-soluble, water⁓insoluble material and containing both gramicidin and tyrocidine. This name is derived from the word Tyrothrix, a generic name first used by Duclaux to designate sporulating aerobic bacterial species, several of which have since been found to exhibit antagonistic activity toward other microorganisms. 1959Sunday Graphic 25 Jan. 4 (Advt.), Antibiotic throat lozenges contain the highly effective antibiotic tyrothricin. 1974M. C. Gerald Pharmacol. xxvi. 453 Tyrothricin proved too toxic for systemic use in animals. |