| 释义 |
tyrosinase Biochem.|ˈtaɪərəs-, taɪˈrɒsɪneɪz|
[a. F. tyrosinase (G. Bertrand 1896, in Compt. Rend. CXXII. 1216): see tyrosine and -ase.]
A copper-containing oxygenase found in many plants and animals which catalyses the formation of quinones from phenols and polyphenols (e.g. melanin from tyrosine) by the addition and then the oxidation of hydroxyl groups.
1896Jrnl. R. Microsc. Soc. 430 In the root of the dahlia and beet, as well as in several fungi..M. G. Bertrand finds a hitherto undescribed diastase, to which he gives the name tyrosinase, from its connection with tyrosin. 1904Proc. R. Soc. LXXIV. 313 An extract can be made from the skins of certain pigmented animals.., which will act upon tyrosin and produce a pigmented substance. This action suggests the presence of a tyrosinase. 1931[see phenolase]. 1974[see polyphenol oxidase s.v. poly- 2]. 1982T. I. Diamondstone in T. M. Devlin Textbk. Biochem. xii. 614/2 Melanin is formed from tyrosine via l-dopa as intermediate; however, the enzyme that catalyzes the formation of l-dopa in this pathway is not tyrosine hydroxylase, but a copper-containing oxygenase known as tyrosinase. |