| 释义 |
triprolidine, n. Pharm.|traɪˈprɒlɪdiːn|
[f. tri- + pyrrolidine n.]
A pyrrolidine derivative and histamine H1 antagonist, C19H22N2 , given (usu. in tablet form as the hydrochloride) to relieve allergic symptoms.
1956Nature 17 Mar. 523/1 The series of spasmolytics, antihistamines and analgesics which we have previously studied, for example, tricyclamol, procyclidine, triprolidine and the thiambutenes. 1966Jrnl. Pharmacol. & Exper. Therap. CLII. 461/2 Triprolidine and bretylium failed to alter the inotropic action of tyramine significantly. 1977Gut XVIII. 91 UK-9040, a derivative of the antihistamine triprolidine, is a potent gastric secretory inhibitor. 1990Jrnl. Clin. Pharmacol. XXX. 572/1 Triprolidine..is a potent H1-histamine receptor antagonist with proven efficacy in treating symptoms associated with a variety of allergic conditions. |