| 释义 |
transfection Microbiology.|trɑːnsˈfɛkʃən, træns-, -nz-|
[f. trans- or transfer n. + infection.]
The introduction of free viral nucleic acid into a cell.
1964Földes & Trautner in Zeitschr. für Vererbungslehre XCV. 61 Infection of cells by the isolated nucleic acid from a virus, resulting in the production of a complete virus will be termed Transfection. 1975Nature 5 June 446/2 The rescue of proviral DNA of Rous sarcoma virus in mammalian cells by ‘transfection’ to permissive chicken cells. 1980Old & Primrose Princ. Gene Manipulation i. 7 Transformation of a cell with DNA from a virus is sometimes referred to as transfection.
So transˈfect v. trans., to infect (a cell) with free viral nucleic acid; transˈfected ppl. a. (said of the cell and of the acid).
1964Zeitschr. für Vererbungslehre XCV. 61 For the plating of transfected cells it is essential to use tryptone plates. 1966Ann. Rev. Microbiol. XX. 394 It appears that the genetic basis for the ability to be transformed or transfected is similar. 1974Nature 22 Nov. 319/2 We tried to transfect ϕX-DNA to various bacteria belonging to the Enterobacteriaceae. 1983Sci. Amer. Jan. 58/2 Investigators have ‘transfected’ cultured cells by exposing them to naked foreign DNA. |