| 释义 |
transdifferentiation, n. Biol.
Brit. |ˌtranzdɪfərɛnʃɪˈeɪʃn|, |ˌtrɑːnzdɪfərɛnʃɪˈeɪʃn|, |ˌtransdɪfərɛnʃɪˈeɪʃn|, |ˌtrɑːnsdɪfərɛnʃɪˈeɪʃn|, U.S. |ˈˌtrænzdɪfəˌrɛn(t)ʃiˈeɪʃ(ə)n|, |ˈˌtræn(t)sdɪfəˌrɛn(t)ʃiˈeɪʃ(ə)n|
[‹ trans- prefix + differentiation n. Compare transdifferentiate v.
Compare the following isolated earlier example in a slightly different sense, translating German Umdifferenzierung:
1968Histochemie 16 119 (heading) Changing adenosine triphosphatase activity in nucleus of cultured chicken heart myoblasts during their transdifferentiation. ]
The change of one type of differentiated or developmentally committed cell into another type; metaplasia.
1971F. C. Kafatos in Endocrinologia Experimentalis 5 101 But what we might call transdifferentiation, the transformation of a cell to a different, equally specialised type, has been difficult to establish with certainty. 1974Tissue & Cell 6 746/1 Labial gland transdifferentiation analogous to that in saturniids also occurs in Manduca. 1993N.Y. Times 31 Aug. c3/4 The Wilm's tumor gene has a broad role in this crucial transdifferentiation event. 2003Science 9 May 865 Adult stem cells..can produce tissues of their own type, and possibly others by a process that developmental biologists call ‘transdifferentiation’. |