| 释义 |
fluoxetine, n. Pharmacol.
Brit. |fluːˈɒksɪtiːn|, U.S. |fluˈwɑksətin|
[‹ flu- (in fluoro- comb. form) + ox- (in oxy- comb. form1) + -etine (perhaps > n.) + -ine (in amine n.)).]
A compound which selectively inhibits the uptake of serotonin in the brain and is given orally (as the hydrochloride) for the treatment of depression; N-methyl-3-(p-trifluoromethylphenoxy)-3-phenylpropylamine, C17H18F3NO.
A proprietary name for this drug is Prozac n.
1975Psychopharmacol. Communications 1 511 (heading) Analgesic effect of fluoxetine hydrochloride.., a specific inhibitor of serotonin uptake. 1989Martindale's Extra Pharmacopoeia (ed. 29) 362/1 Fluoxetine..is reported to cause fewer antimuscarinic side-effects than tricyclic antidepressants. 1993Guardian 21 Sept. ii. 16/1 Prozac (known generically as fluoxetine) is the latest US craze, favoured by one in five people who take anti-depressants. 2000Daily Tel. 11 Jan. 26/2 Prozac's owner..no longer has sole right to the product and Hertfordshire-based Bioglan Pharma yesterday stepped in with a cheaper copy. Bioglan's version uses the same active ingredient—Fluoxetine. |