| 释义 |
thiabendazole Vet. Med. and Pharm.|θaɪəˈbɛndəzəʊl|
[f. thia(zole s.v. thio- 1 + ben(zimi)dazole f. benzene + imide + azo- + -ole.]
An anthelmintic used in veterinary and human medicine, esp. against intestinal nematodes.
1961H. D. Brown et al. in Jrnl. Amer. Chem. Soc. LXXXIII. 1765/1, 2-(4′-Thiazolyl)-benzimidazole (I, generic name: thiabendazole) was outstanding in anthelmintic activity. 1970W. H. Parker Health & Dis. in Farm Animals xx. 265 New worm medicines are appearing frequently. At the present time the choice is likely to be either thiabendazole or tetramisole. 1978R. B. Scott Price's Textbk. Pract. Med. (ed. 12) ii. 236/2 Thiabendazole has been shown to destroy adult female worms [sc. Trichinella spiralis] and larvae but must be used with extreme caution because it may precipitate serious reactions with anorexia, nausea, headache, giddiness, and drowsiness, possibly as a result of allergy to dead larvae. |