| 释义 |
ˈread-through
Also readthrough, read through.
[f. read v.]
1. An act of reading through; spec. Theatr., an initial rehearsal at which actors read their parts from scripts.
1961A. Wilson Old Men at Zoo ii. 95 She has to go to a read-through whatever that may be. 1963E. Humphreys Gift ii. i. 209 He was late for the read through... Started talking loudly to the actress next to him and greeting everybody when we had already begun to read. 1966‘O. Norton’ School of Liars vii. 113, I..came back for the first read-through, and the acting notes. 1971Guardian 3 July 9/3 ‘This script is a mess..’ said Adrienne Corri the other day at a read-through for my TV series. 1976J. Grenfell Joyce Grenfell requests Pleasure xvi. 230 Our spirits went up and down..after the usual enthusiastic read-through when the material seemed so original and imaginative.
2. Biochem. The continued transcription of genetic material by RNA polymerase that has overrun a termination sequence.
[1970Goff & Minkley in L. Silvestri RNA-Polymerase & Transcription 134 One interesting interpretation of these results is that the largest RNA class is produced when rho fails to function at the first termination signal used in vivo and the polymerase reads through to a second ‘stop signal’.] 1970A. A. Travers in Nature 14 Mar. 1011/2 (caption) Fig. 3. Readthrough by E. coli σ initiated RNA polymerase into sequences transcribed by σT4 initiated polymerase. 1971Ibid. 15 Dec. 207/2 These sequence data strongly suggest that the IIb protein is a read-through product resulting from polypeptide chain elongation. 1978Ibid. 30 Mar. 417/2 One of these..is the only oligonucleotide consistent with transcriptional ‘read-through’ of the termination site. |