释义 |
succinylsulphathiazole Pharm.|ˌsʌksɪnaɪlsʌlfəˈθaɪəzəʊl| Also -sulf-. [f. succinyl + sulphathiazole.] A poorly absorbed sulphonamide derivative which is used in the treatment of gastrointestinal infections and is inactive until hydrolysed to sulphathiazole in the body; 4′-(thiazol-2-ylsulphamoyl)-succinanilic acid, C3H2NS·NH·SO2·C6H4·NH·CO·(CH2)2COOH.
1941Proc. Soc. Exper. Biol. & Med. XLVIII. 129 (heading) Succinyl sulfathiazole, a new bacteriostatic agent locally active in the gastrointestinal tract. 1981H. J. Rogers et al. Textbk. Clinical Pharmacol. xix. 647 Only 5–10% of these drugs are absorbed... Examples are phthalylsulphathiazole and succinylsulphathiazole, both of which hydrolyse to sulphathiazole. |