| 释义 |
subtilin Pharm.|ˈsʌbtɪlɪn|
[f. L. subtil-is slender + -in1.]
Any of a group of polypeptides of differing antibiotic activity (subtilin A, subtilin B, subtilin C) derived by culture from Bacillus amyloliquefaciens (orig. identified as B. subtilis), the most potent of which are used against Gram-positive bacteria and certain pathogenic fungi.
1944Jansen & Hirschmann in Arch. Biochem. IV. 298 The substance thus differing from tyrothricin has been named subtilin by the authors. 1948Sun (Baltimore) 9 Jan. 5/1 Recently publicized ‘wonder drugs’ include..subtilin. 1948C. H. Hassal in Nature 28 Feb. 318/1 By use of the latter procedure, followed by dilution of the alcoholic extract with adjustment of the pH to 2·3, an active concentrate, which we will term subtilin C, was obtained. 1966McGraw-Hill Encycl. Sci. & Technol. XIII. 230/2 Subtilin A, the major component of the subtilin family, is separated by partition chromatography. 1976J. S. Glasby Encycl. Antibiotics 334/1 A further antibiotic isolated from cultures of Bacillus subtilis, subtilin may be produced by both surface and submerged growth on various media. The associated antibiotic subtilin C..appears to be identical..in all respects except that it gives no colour reaction with FeCl3 solution. |