| 释义 |
ranitidine, n. Pharm.|ræˈnɪtɪdiːn, -ˈnaɪ-|
[f. ranit-, blend of furan n. and nitro-, + -idine.]
A substituted furan, C13H22N4O3S , with histamine H2-receptor blocking properties, given (usu. in tablet form) as the hydrochloride to inhibit the secretion of gastric acid in the treatment of peptic ulcers and related conditions.
1979Lancet 10 Feb. 320/2 Ranitidine may have even fewer non-specific adverse side-effects than those reported occasionally for cimetidine. 1981Gut XXII. s4/1 The degree of acid inhibition comparable with that produced during treatment with four daily doses of cimetidine was..produced by a twice daily dose of ranitidine. 1985Investors Chron. 8 Nov. 61/1 (Advt.), Sales of ranitidine by Glaxo subsidiaries during the year increased by over {pstlg}180 million. 1989Encycl. Brit. XVII. 516/2 The H2-receptor antagonist drugs, such as cimetidine and ranitidine, rapidly established a place in the treatment of conditions involving the hypersecretion of gastric acid. |