英语词汇“dideoxycytidine”的英英意思、用法、释义、翻译、读音、例句、短语、词组-英语词典

单词	dideoxycytidine
释义	dideoxycytidine, n. Pharm.\|ˌdaɪdɪɒksɪˈsaɪtɪdiːn\| [f. di-² + deoxy- + cytidine n.] Either of two isomeric pyrimidine nucleoside analogues having the formula C₉H₁₃N₃O₃ ; spec. (in full *2′,3′-dideoxycytidine) a compound which inhibits the replication of certain viruses (including HIV) and has been used experimentally in the treatment of HIV infection. Abbrev. ddc*. 1965Jrnl. Org. Chem. XXX. 3068/1 Hydrogenation..gave the desired 2′,5′-dideoxycytidine as the hydriodide salt.Ibid. 3069/1 A desirable derivative of 2′-deoxycytidine of potential biological significance is 2′,3′-dideoxycytidine.1980Jrnl. Biol. Chem. CCLV. 11850/2 Dideoxycytidine triphosphate..is a potent inhibitor of DNA polymerases β and γ.1988New Scientist 21 Jan. 28/1 A preliminary trial of dideoxycytidine (ddC) in 20 patients with AIDS or severe disease caused by HIV infection.1992Independent 1 Feb. 6/4 There is a third anti-retroviral, DDC (dideoxycytidine), and now large-scale trials into combination therapy..are under way.
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